Telomeresare the structures at the end of chromosomes used to protect them from deterioration. As we age, our chromosomes shorten leading some scientists to believe this corresponds with aging and ultimately our death.
So what does a shorter telomere mean health-wise? In men, shorter telomeres can lead to pulse pressure and pulse wave velocity, stiffer atherosclerotic arteries, idopathic pulmonary fibrosis, and bone marrow failure. Some diseases with premature aging, such as Werner syndrome, are associated with telomere dysfunction.
Telomerase is an enzyme that protects the telomeres and can actually synthesize new telomere length. If you activate this enzyme in mice, reversal in organ atrophy, brain atrophy, hair greying, and osteoporosis was seen.
Patients who had a low-fat, whole food, plant-based diet with moderate aerobic exercise and mediation and relaxation had not only less stress and improved LDL's but improved telomerase activity. Smoking is known to shorten telomere length as well.
So while it may seem obvious that a person who smokes, doesn't exercise and is under psychological stress will likely age worse than one who lives a healthy, stress-free lifestyle, knowing science is starting to support this view should lead us all to strive to make the time and effort to do our best to live the healthiest lives we can.
As Dr. Shah sees patients from all over, he is often asked the difference in aesthetic between European and American noses. From Dr. Shah:
First of all, there is such a wide difference amongst patients within Europe and the United States that it is not possible to distinguish one type of aesthetic versus the other. European patients as a whole tend to favor as natural appearance as possible. Patients do not want to look overly done and look like they have had plastic surgery. This is definitely true for American patients as well, but some Americans prefer a more stylistic version of their nose. An example of this is seen in the angle of the nose or how "up" it may look. European patients often prefer this angle to be closer to 90 degrees while some American patients, particularily females, will want a shorter nose. Tailoring your operation to both the face as well as the person is one important step to achieving successful outcomes.
Recent large studies from the American Heart Association have made some changes to the guidelines on diet. In particular, the diet guideline suggested that fruits, fish, legumes, poultry and vegetables were acceptable. But perhaps more controversially, the diet stated that nuts of all types were recommended. Not surprising, red meat, sugar, trans fats sodium and saturated fats were to be restricted.
Evidence of fruit and vegetable consumption in decreasing heart disease was see in studying around 100,000 men and women in a Nurse's Health Study and Health Professional Follow-Up Study. Of significance were that variety was more important than quantity.
Nut consumption was shown to have decreased risk in heart disease. In fact patients with more nut consumption had corresponding lower heart disease than those without in a study of more than 3 million person-years of Nurse's Health Study and the Health Professionals Follow-up Study with a 20% reduction in mortality in subjects who eat nuts 7 or more times a week versus 7% reduction in mortality in those who did not eat nuts.
Meat consumption, in particular processed meat and red meat, had significantly higher mortality especially cardiovascular diseases. Most of the data from meat consumption was taken from an analysis of nearly 500,000 participants in the European Prospective Investigation Into Cancer and Nutrition trial. The study stated that red meat consumption over 5.6 ounces per day had 44% all-cause mortality. An additional trial in the American Journal of Clinical Nutrition noted that individuals with a 20 year history of low meat consumption lived an additional 3.6 years longer.
So what is the take home points of these recent large trials? First of all, nuts, even though they may be high in fats, are considered heart healthy. Red meat is not. An ideal diet for prolonging longevity on current studies would be a highly varied diet high in fruits, vegetables with low red meat consumption.
Perhaps an underappreciated aspect of male youthfullness is in the lips. Fuller male lips are often seen in younger males and tends to decrease in size with age. While an overly full top lip is not an attractive option in either male or female adding a subtle amount of filler can help be a tasteful detail in making a male face look youner and more attractive.
Our understanding of the aging process behind the perioral area is constantly being updated. Over time, many of us lose volume, not only within the red portion of the lip, but as a result of bony loss around our dental region. This combination can make the white portion of the lip (the area between the red lip and the nose) appear longer.
Facial filler can help add volume to the red lip and can help balance out the overly long upper lip (white portion of the lip). Subtle enhancments can help the face appear more attractive and appealing on multiple levels. Lip enhancement in males is one such area.